Lamivudine

(Shown in complex with Nevirapine instead)

Residue 41 44 65 67 69 70 74 75 77 103 115
Mutations M L D A E R K N D S T D N K R E V L I V T M L F N K F Y M
Citation M L L L L L L M D/A D/A D D R K R R R R R R R R R R R R R N N N N N N/S T D N K R R R E R K L V L V V V V V I I/V L L/F L N N F F M

Residue 116 118 151 184 210 215 219
Mutations Y F I V M Q V M I A W L F T Y F D C Q K E
Citation Y I I I I I I M M Q M M M M M V V V V I/V V V V V I/V V V V V V V V V V M V V I/V V V V V V V V V V V V V V V V I V V V V V I/V I/V V V I/V I/V V V V V M V V V I V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V V/I V V V V/I V V/I V V/I V V A V V V V V V V V V V I/V V V V V V V V V V/I V M/V V V M/V W F T Y/F Y/F Y Y Y Y/F Y/F Y D T Y/C Y Q E Q K

wild type residues in bold
model based on 1LW0 (in complex with Nevirapine)
actual ligand shown at bottom

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